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Generic and Specific Adaptive Responses of<i>Streptococcus pneumoniae</i>to Challenge with Three Distinct Antimicrobial Peptides, Bacitracin, LL-37, and Nisin

17 Nov 2009

Abstract excerpt

To investigate the response of Streptococcus pneumoniae to three distinct antimicrobial peptides (AMPs), bacitracin, nisin, and LL-37, transcriptome analysis of challenged bacteria was performed. Only a limited number of genes were found to be up- or downregulated in all cases. Several of these common highly induced genes were chosen for further analysis, i.e., SP0385-SP0387 (SP0385-0387 herein), SP0912-0913,...

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PMID: 19917758
DOI: 10.1128/aac.00769-09

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