Article
Expression of unmutated VH genes is a detrimental prognostic factor in chronic lymphocytic leukemia
1 Jul 2000
Abstract excerpt
Chronic lymphocytic leukemia (CLL) is recognized as a heterogeneous disease.[1][1] Although the clinical staging systems (Rai et al[2][2] and Binet et al[3][3]) provide useful methods of assessing patient prognosis, they do not provide an understanding of the basis of the heterogeneity. CLL cells
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