CD38 expression is a poor predictor for VH gene mutational status and prognosis in chronic lymphocytic leukemia

Abstract excerpt

Chronic lymphocytic leukemia (CLL) has traditionally been viewed as a neoplastic proliferation of naive B cells of the mantle zone, but this view is now changing, with reports of somatically mutated immunoglobulin (Ig) variable heavy chain (VH) genes in CLL.[1][1],[2][2] Recently, Hamblin et al[1][1

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