Article
Clinical and therapeutic implications of the mutational status of IgVH in patients with chronic lymphocytic leukemia.
Cancer - 1 Sept 2008
Kharfan-Dabaja Mohamed A, Chavez Julio C, Khorfan Khadija A, Pinilla-Ibarz Javier
Abstract excerpt
The past 2 decades have brought major advances to clinicians' understanding of the complexities of chronic lymphocytic leukemia (CLL). Novel biologic and genetic markers are providing tools for more accurate prediction of responses, disease progression, and survival of patients across different stages of CLL. Several multivariate analyses have confirmed unmutated IgVH to be an independent adverse prognostic...
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