Article
beta(2)-adrenergic receptor Arg16/Arg16 genotype is associated with reduced lung function, but not with asthma, in the Hutterites.
American journal of respiratory and critical care medicine - 1 Aug 2000
Summerhill E, Leavitt S A, Gidley H, Parry R, Solway J, Ober C
Abstract excerpt
In a genome-wide screen for asthma loci in the Hutterites, a marker locus on chromosome 5q23-31 showed evidence of linkage to asthma (C. Ober and colleagues, Hum. Molec. Genet. 1998;7:1393). To determine whether the beta(2)-adrenergic receptor (beta(2)AR) gene is the 5q-linked asthma locus in the Hutterites, we genotyped this sample for polymorphisms in the beta(2)AR gene. Neither the Arg16Gly nor Gln27Glu...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.