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Article

Spectroscopic comparison of the heme active sites in WT KatG and its S315T mutant.

Biochemistry - 15 Aug 2000

Lukat-Rodgers G S, Wengenack N L, Rusnak F, Rodgers K R

Abstract excerpt

KatG, the catalase-peroxidase from Mycobacterium tuberculosis, has been characterized by resonance Raman, electron spin resonance, and visible spectroscopies. The mutant KatG(S315T), which is found in about 50% of isoniazid-resistant clinical isolates, is also spectroscopically characterized. The electron spin resonance spectrum of ferrous nitrosyl KatG is consistent with a proximal histidine ligand. The Fe-His...

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PMID: 10933819
DOI: 10.1021/bi0006870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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