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Article

Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription.

The Journal of biological chemistry - 7 Aug 1998

Sawaya B E, Khalili K, Mercer W E, Denisova L, Amini S

Abstract excerpt

Transcription of the human immunodeficiency virus type-1 (HIV-1) genome is controlled by cooperative interaction of viral encoded proteins and host regulatory proteins. In this study, we have examined the capacity of the viral auxiliary protein, Vpr, to modulate transcriptional activity of the HIV-1 promoter sequence located within the long terminal repeat (LTR). We demonstrate that ectopic expression of Vpr in...

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Source

Identifiers

PMID: 9685344
DOI: 10.1074/jbc.273.32.20052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription.PMID 9685344Read ↗

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