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Article

Human immunodeficiency virus vpr product is a virion-associated regulatory protein.

Journal of virology - 1 Jun 1990

Cohen E A, Dehni G, Sodroski J G, Haseltine W A

Abstract excerpt

The vpr product of the human immunodeficiency virus type 1 (HIV-1) acts in trans to accelerate virus replication and cytopathic effect in T cells. Here it is shown that the HIV-1 viral particle contains multiple copies of the vpr protein. The vpr product is the first regulatory protein of HIV-1 t...

Topics

CD4 Antigens
Codon
Gene Products, vpr
Genes, Viral
Genotype
HIV-1
Humans
Molecular Weight
Restriction Mapping
Retroviridae Proteins
T-Lymphocytes
Trans-Activators
Transfection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virion

Virus Replication

vpr Gene Products, Human Immunodeficiency Virus

Source

Open in PubMed Open full text

Identifiers

PMID: 2139896
DOI: 10.1128/JVI.64.6.3097-3099.1990
PMCID: PMC249501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2139896-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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