Article
Human immunodeficiency virus vpr product is a virion-associated regulatory protein.
Journal of virology - 1 Jun 1990
Cohen E A, Dehni G, Sodroski J G, Haseltine W A
Abstract excerpt
The vpr product of the human immunodeficiency virus type 1 (HIV-1) acts in trans to accelerate virus replication and cytopathic effect in T cells. Here it is shown that the HIV-1 viral particle contains multiple copies of the vpr protein. The vpr product is the first regulatory protein of HIV-1 to be found in the virus particle. This observation raises the possibility that vpr acts to facilitate the early steps...
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