Article
Growth of Brucella abortus in macrophages from resistant and susceptible mouse strains.
Clinical and experimental immunology - 1 Aug 2000
Sathiyaseelan J, Jiang X, Baldwin C L
Abstract excerpt
C57Bl/10 mice have a superior ability to control chronic infections with virulent strains of the intracellular bacteria Brucella abortus compared with BALB/c mice. While a number of differences in the cytokines produced by lymphocytes following infection of these two strains of mice have been shown, macrophages have not been evaluated for their role in conveying relative resistance. The importance of macrophages...
Topics
- Animals
- Anti-Bacterial Agents
- Brucella abortus
- Carrier Proteins
- Cation Transport Proteins
- Cells, Cultured
- Female
- Genetic Predisposition to Disease
- Gentamicins
- Immunity, Innate
- Interferon-gamma
- Iron
- Macrophages, Peritoneal
- Membrane Proteins
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred Strains