Article
In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice.
PLoS pathogens - 1 Jan 2012
Copin Richard, Vitry Marie-Alice, Hanot Mambres Delphine, Machelart Arnaud, De Trez Carl, Vanderwinden Jean-Marie, Magez Stefan, Akira Shizuo, Ryffel Bernhard, Carlier Yves, Letesson Jean-Jacques, Muraille Eric
Abstract excerpt
Brucella are facultative intracellular bacteria that chronically infect humans and animals causing brucellosis. Brucella are able to invade and replicate in a broad range of cell lines in vitro, however the cells supporting bacterial growth in vivo are largely unknown. In order to identify these, we used a Brucella melitensis strain stably expressing mCherry fluorescent protein to determine the phenotype of...
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