Article
Survival of Brucella abortus S19 and other Brucella spp. in the presence of oxidative stress and within macrophages.
Folia microbiologica - 1 Oct 2020
Jacob Jens, Finke Antje, Mielke Martin
Abstract excerpt
The evolutionary "success" of the genus Brucella depends on the ability to persist both in the environment as well as inside of even activated macrophages of the animal host. For that, the Brucellae produce catalase and superoxide dismutase to defend against oxidative stress. Since the deletion of the mglA gene in the B. abortus S19 vaccine strain resulted not only in an increased tolerance to H2O2 but also in...
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