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Article

HGF/scatter factor selectively promotes cell invasion by increasing integrin avidity.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2000

Trusolino L, Cavassa S, Angelini P, Andó M, Bertotti A, Comoglio P M, Boccaccio C

Abstract excerpt

Hepatocyte growth factor/scatter factor (HGF/SF) controls a genetic program known as 'invasive growth', which involves as critical steps cell adhesion, migration, and trespassing of basement membranes. We show here that in MDA-MB-231 carcinoma cells, these steps are elicited by HGF/SF but not by epidermal growth factor (EGF). Neither factor substantially alters the production or activity of extracellular matrix...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10928998
DOI: 10.1096/fj.14.11.1629

Genes

HGF
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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