Effect of Angiotensin II on Hematopoietic Progenitor Cell Proliferation

doi:10.1634/stemcells.18-4-287

Article

Effect of Angiotensin II on Hematopoietic Progenitor Cell Proliferation

1 Jul 2000

Abstract excerpt

Angiotensin II (AII) induced the proliferation of hematopoietic progenitor cells (HPC) isolated from murine bone marrow or human cord blood. The formation of colonies with more than 50 cells increased approximately five-sevenfold in cultures of murine lineage-negative (Lin(-)) bone marrow cells both in the presence (day 10) and absence (day 13) of colony-stimulating factors (CSF). This could be blocked with...

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