Purification and partial characterization of a human hematopoietic precursor population.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Purification and partial characterization of a human hematopoietic precursor population.

Blood - 15 May 1991

Smith C, Gasparetto C, Collins N, Gillio A, Muench M O, O'Reilly R J, Moore M A

Abstract excerpt

This study reports the development of an assay, the Pre-colony-forming unit (CFU) assay, which detects human hematopoietic precursors. The Pre-CFU assay is based on the observation that precursors to CFU-granulocyte-macrophage (CFU-GM) that are undetectable in clonogenic assays differentiate into CFU-GM preferentially following treatment in suspension culture with recombinant human interleukin-1 alpha (rhIL-1...

Topics

Animals
Antigens, CD34
Antigens, Differentiation
Bone Marrow
Bone Marrow Cells
Cell Division
Cell Separation
Cell Survival
Cells, Cultured
Colony-Forming Units Assay
Cyclophosphamide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fluorouracil

Granulocytes

Hematopoietic Stem Cells

Humans

Interleukin-3

Macaca

Macrophages

Source

Open in PubMed

Identifiers

PMID: 1709369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1709369-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Purification and partial characterization of a human hematopoietic precursor population.PMID 1709369Read ↗

Prospective isolation of human clonogenic common myeloid progenitorsSemantic proximity Read ↗

Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factorSemantic proximity Read ↗

A newly discovered class of human hematopoietic cells with SCID-repopulating activity.Semantic proximity Read ↗

Phenotypic analysis and characterization of CD34+ cells from normal human bone marrow, cord blood, peripheral blood, and mobilized peripheral blood from patients undergoing autologous stem cell transplantation.Semantic proximity Read ↗

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity.Semantic proximity Read ↗

C1qR <sub>p</sub> defines a new human stem cell population with hematopoietic and hepatic potentialSemantic proximity Read ↗

Establishment of serum-free pre-colony forming unit assays for differentiation of primitive hematopoietic progenitors: serum induces early macrophage differentiation and inhibits early erythroid differentiation of CD34++CD38- cells.Semantic proximity Read ↗

Characterization of human hematopoietic cells with short-lived in vivo repopulating activity.Semantic proximity Read ↗

Phenotypic and functional analyses of CD34NEG hematopoietic precursors from mobilized peripheral blood.Semantic proximity Read ↗

Functional Heterogeneity of Human CD34+ Cells Isolated in Subcompartments of the G0 /G1 Phase of the Cell CycleSemantic proximity Read ↗

Molecular Analysis of Primitive Hematopoietic Cell Proliferation Control Mechanisms<sup>a</sup>Semantic proximity Read ↗

Further phenotypic characterization and isolation of human hematopoietic progenitor cells using a monoclonal antibody to the c-kit receptor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.