Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cognitive decline in patients with familial Alzheimer's disease associated with E280a presenilin-1 mutation: a longitudinal study.

Journal of clinical and experimental neuropsychology - 1 Aug 2000

Rosselli M C, Ardila A C, Moreno S C, Standish V C, Arango-Lasprilla J C, Tirado V M, Ossa J M, Goate A M, Kosik K S, Lopera F

Abstract excerpt

Few longitudinal studies have been carried out to investigate the cognitive decline in early onset of familial Alzheimer's disease (FAD). In this study 12 patients with FAD (M age = 49.61 years, SD = 4.99), 10 patients with sporadic Alzheimer's disease (SAD) (M age = 71.40, SD =10.00), and 15 matched normal controls (M age = 45.01, SD = 7.24) were selected. A comprehensive neuropsychological battery was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Cognition Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Longitudinal Studies

Share to Membrane Proteins

Share to Memory

Share to Neuropsychological Tests

Share to Presenilin-1

Source

Identifiers

PMID: 10923058
DOI: 10.1076/1380-3395(200008)22:4;1-0;FT483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cognitive decline in patients with familial Alzheimer's disease associated with E280a presenilin-1 mutation: a longitudinal study.PMID 10923058Read ↗

Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study.Semantic proximity Read ↗

Cognitive Outcomes in Autosomal-Dominant Alzheimer's Disease: A Comprehensive Review from a Colombian Kindred with the Presenilin-1 E280A Mutation.Semantic proximity Read ↗

Neuropsychological study of familial Alzheimer's disease caused by mutation E280A in the presenilin 1 gene.Semantic proximity Read ↗

Mild cognitive impairment--an early stage of Alzheimer's disease?Semantic proximity Read ↗

Enhanced brain activity may precede the diagnosis of Alzheimer's disease by 30 years.Semantic proximity Read ↗

Early onset Alzheimer's disease is associated with a distinct neuropsychological profile.Semantic proximity Read ↗

Clinical and psychological characteristics of the initial cohort of the Dominantly Inherited Alzheimer Network (DIAN).Semantic proximity Read ↗

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.Semantic proximity Read ↗

Natural history of cognitive decline in the old old.Semantic proximity Read ↗

A comparison of familial and sporadic Alzheimer's diseaseSemantic proximity Read ↗

Clinical and psychometric distinction of frontotemporal and Alzheimer dementias.Semantic proximity Read ↗

Presymptomatic cognitive decline in familial frontotemporal dementia: A longitudinal study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.