Article
Natural history of cognitive decline in the old old.
Neurology - 13 May 2003
Howieson D B, Camicioli R, Quinn J, Silbert L C, Care B, Moore M M, Dame A, Sexton G, Kaye J A
Abstract excerpt
OBJECTIVE: To prospectively examine the occurrence and outcome of cognitive decline in healthy, community-dwelling elders. METHODS: Ninety-five elders (mean age 84 years) who at entry had no cognitive impairment were followed for up to 13 years. Cognitive decline was defined as obtaining either a Clinical Dementia Rating (CDR) = 0.5 or Mini-Mental State Examination (MMSE) score < 24 on two examinations. RESULTS:...
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