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Article

Neuropsychological study of familial Alzheimer's disease caused by mutation E280A in the presenilin 1 gene.

American journal of Alzheimer's disease and other dementias - 1 Jan 2000

Arango Lasprilla Juan Carlos, Iglesias Jaime, Lopera Francisco

Abstract excerpt

In Antioquia, Colombia, investigators have recently discovered the largest family with the E280A mutation in the presenilin 1 gene that causes one type of familial Alzheimer's disease (FAD). The current study compares two groups within this family: those diagnosed with Alzheimer's disease (AD) in its early stage (nine subjects) and relatives (carriers) who did not show any signs of dementia (nine subjects). A...

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Identifiers

PMID: 12811988
DOI: 10.1177/153331750301800306
PMCID: PMC10833779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Neuropsychological study of familial Alzheimer's disease caused by mutation E280A in the presenilin 1 gene.PMID 12811988Read ↗

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The Alzheimer's prevention initiative composite cognitive test score: sample size estimates for the evaluation of preclinical Alzheimer's disease treatments in presenilin 1 E280A mutation carriers.Semantic proximity Read ↗

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