Article
Sequence comparison of aflR from different Aspergillus species provides evidence for variability in regulation of aflatoxin production.
Fungal genetics and biology : FG & B - 1 Feb 2003
Ehrlich Kenneth C, Montalbano Beverly G, Cotty Peter J
Abstract excerpt
Aflatoxin contamination of foods and feeds is a world-wide agricultural problem. Aflatoxin production requires expression of the biosynthetic pathway regulatory gene, aflR, which encodes a Cys6Zn2-type DNA-binding protein. Homologs of aflR from Aspergillus nomius, bombycis, parasiticus, flavus, and pseudotamarii were compared to investigate the molecular basis for variation among aflatoxin-producing taxa in the...
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