Article
Molecular characterization of the afl-1 locus in Aspergillus flavus.
Applied and environmental microbiology - 1 Aug 1995
Woloshuk C P, Yousibova G L, Rollins J A, Bhatnagar D, Payne G A
Abstract excerpt
An unusual mutation at the afl-1 locus, affecting aflatoxin biosynthesis in Aspergillus flavus 649, was investigated. The inability of strain 649 to produce aflatoxin was found to be the result of a large (greater than 60 kb) deletion that included a cluster of aflatoxin biosynthesis genes. Diploids formed by parasexual crosses between strain 649 and the aflatoxigenic strain 86 did not produce aflatoxin,...
Topics
- Aflatoxins
- Aspergillus flavus
- Gene Deletion
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Multigene Family
- Mutation
