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Article

Signal transduction. FasL binds preassembled Fas.

Science (New York, N.Y.) - 30 Jun 2000

Golstein P

Abstract excerpt

The binding of a ligand to its receptor has always been viewed as the trigger for signal transduction to ensue. However, as Golstein explains in his Perspective, new findings (Chan et al. and Siegel et al.) suggest that the Fas receptor preassembles into trimers without the help of its ligand, an...

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Identifiers

PMID: 10917832
DOI: 10.1126/science.288.5475.2328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10917832-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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