Article
Infection of mesangial cells with HIV and SIV: identification of GPR1 as a coreceptor.
Kidney international - 1 Aug 2000
Tokizawa S, Shimizu N, Hui-Yu L, Deyu F, Haraguchi Y, Oite T, Hoshino H
Abstract excerpt
BACKGROUND: Mesangial cells are an important component of the glomerulus. Dysfunction of mesangial cells is thought to be involved in the development of human immunodeficiency virus type 1 (HIV-1)-associated nephropathy (HIVAN). HIVAN is a structural renal failure frequently observed in patients with acquired immune deficiency syndrome. However, the susceptibility of mesangial cells to HIV-1 is disputable. More...
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