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Article

G protein-coupled receptors in HIV and SIV entry: New perspectives on lentivirus–host interactions and on the utility of animal models

1 Jun 1998

Abstract excerpt

Entry of primate lentiviruses into target cells has recently been shown to depend upon the interaction of the viral envelope glycoprotein with CD4 and one or more members of the G protein-coupled receptor (GPCR) family of transmembrane proteins. In vivo, the transmission of HIV-1 infection generally requires viral strains that utilise chemokine recep- tor CCR5, and these strains prevail during the early course of...

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Identifiers

PMID: 9653049
DOI: 10.1006/smim.1998.0134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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