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Article

Gene profiling approach in the analysis of lymphotoxin and TNF deficiencies.

Journal of leukocyte biology - 1 Jul 2000

Shakhov A N, Lyakhov I G, Tumanov A V, Rubtsov A V, Drutskaya L N, Marino M W, Nedospasov S A

Abstract excerpt

Mice with combined lymphotoxin-alpha (LTalpha) and tumor necrosis factor (TNF) deficiencies show defects in the structure of peripheral lymphoid organs such as spleen, lymph nodes, and gut-associated lymphoid tissues. To identify genes associated with this defective phenotype in spleen, we applied a gene profiling approach, including subtractive cloning and gene array hybridizations, to mice with combined TNF/LT...

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Identifiers

PMID: 10914503

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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