Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endotoxin induction of murine metallothionein gene expression.

1 Sept 1990

Abstract excerpt

Bacterial endotoxin-lipopolysaccharide (LPS) rapidly induced hepatic metallothionein (MT) mRNA levels in the LPS-sensitive CD-1 strain of mice. This LPS effect was severely attenuated in the LPS-resistant C3H/HeJ strain of mice, but could be mimicked by injection of human recombinant interleukin-1 alpha (IL-1 alpha) or human recombinant tumor necrosis factor (TNF-alpha). In the CD-1 strain, LPS induction of MT...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child Nutrition and Water Access
Share to Iron Metabolism and Disorders
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2203773
DOI: 10.1016/s0021-9258(18)77251-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Endotoxin induction of murine metallothionein gene expression.PMID 2203773Read ↗

Down-regulation of mouse organic anion-transporting polypeptide 4 (Oatp4; Oatp1b2; Slc21a10) mRNA by lipopolysaccharide through the toll-like receptor 4 (TLR4).Semantic proximity Read ↗

Alterations in tumor necrosis factor-alpha expression by hepatic macrophages following acute cholestatic liver injury.Semantic proximity Read ↗

Pro‐ and Anti‐Inflammatory Gene Expression in the Murine Small Intestine and Liver After Chronic Exposure to AlcoholSemantic proximity Read ↗

Gene profiling approach in the analysis of lymphotoxin and TNF deficiencies.Semantic proximity Read ↗

Differential induction of interleukin-I beta mRNA in the brain parenchyma of Lewis and Fischer rats after peripheral injection of lipopolysaccharides.Semantic proximity Read ↗

Hepatic Thrombopoietin mRNA Is Increased in Acute InflammationSemantic proximity Read ↗

Induction of hepatic metallothionein synthesis by endoplasmic reticulum stress in mice.Semantic proximity Read ↗

Differential Expression of Inflammatory Cytokines and Stress Genes in Male and Female Mice in Response to a Lipopolysaccharide ChallengeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.