Molecular variations in the calcium-sensing receptor in relation to sodium balance and presence of hypertension in blacks and whites.

doi:10.1016/s0895-7061(99)00285-x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Molecular variations in the calcium-sensing receptor in relation to sodium balance and presence of hypertension in blacks and whites.

American journal of hypertension - 1 Jun 2000

Pratt J H, Ambrosius W T, Wagner M A, Maharry K

Abstract excerpt

Sodium (Na) excretion is to an extent tied to calcium (Ca) excretion; increases in Ca result in increased Na excretion. We hypothesized that molecular variation in the calcium-sensing receptor (CaSR), which imparts certain of the influences of extracellular Ca, might be related to differences in Na balance and blood pressure. We further hypothesized that such an influence by CaSR is more pronounced in blacks than...

Topics

Adolescent
Adult
Aldosterone
Black People
Blood Pressure
Blood Pressure Monitoring, Ambulatory
Calcium
Child
Female
Gene Frequency
Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genotype

Humans

Hypertension

Indiana

Longitudinal Studies

Male

Source

Open in PubMed

Identifiers

PMID: 10912749
DOI: 10.1016/s0895-7061(99)00285-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular variations in the calcium-sensing receptor in relation to sodium balance and presence of hypertension in blacks and whites.PMID 10912749Read ↗

Association of the calcium-sensing receptor gene with blood pressure and urinary calcium in African-Americans.Semantic proximity Read ↗

The role of the calcium-sensing receptor in disorders of abnormal calcium handling and cardiovascular disease.Semantic proximity Read ↗

A986S polymorphism of the calcium-sensing receptor and circulating calcium concentrations.Semantic proximity Read ↗

Association between total serum calcium and the A986S polymorphism of the calcium-sensing receptor gene.Semantic proximity Read ↗

Racial difference in the activity of the amiloride-sensitive epithelial sodium channel.Semantic proximity Read ↗

Intracellular cations and hypertension in blacks.Semantic proximity Read ↗

Salt sensitivity: a review with a focus on non-Hispanic blacks and Hispanics.Semantic proximity Read ↗

Epithelial sodium channel allele T594M is not associated with blood pressure or blood pressure response to amiloride.Semantic proximity Read ↗

Blood ionized calcium is associated with clustered polymorphisms in the carboxyl-terminal tail of the calcium-sensing receptor.Semantic proximity Read ↗

Alpha 2-adrenergic receptor gene polymorphism and hypertension in blacks.Semantic proximity Read ↗

Systemic hypertension in blacks: an overview of current concepts of pathogenesis and management.Semantic proximity Read ↗

Association study of eight candidate genes with renin status in mild-to-moderate hypertension in patients of African ancestry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.