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Article

Association of the calcium-sensing receptor gene with blood pressure and urinary calcium in African-Americans.

The Journal of clinical endocrinology and metabolism - 1 Mar 2009

Jung Jeesun, Foroud Tatiana M, Eckert George J, Flury-Wetherill Leah, Edenberg Howard J, Xuei Xiaoling, Zaidi Syed-Adeel, Pratt J Howard

Abstract excerpt

CONTEXT: Calcium binding to the Ca-sensing receptor (CASR) expressed in thick ascending limb inhibits the Na,K,2Cl cotransporter, which decreases sodium reabsorption and secondarily decreases Ca reabsorption. CASR gene variants could influence blood pressure (BP) by affecting Na retention. OBJECTIVE: The objective of the study was to determine whether variations in CASR associated with BP in African-Americans, an...

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Source

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Identifiers

PMID: 19066294
DOI: 10.1210/jc.2008-1861
PMCID: PMC2681276

Genes

CASR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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