Article
Association study of eight candidate genes with renin status in mild-to-moderate hypertension in patients of African ancestry.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners - 1 Jan 2000
Tiago A D, Nkeh B, Candy G P, Badenhorst D, Defterios D, Brooksbank R, Nejthardt M, Luker F, Milne J, Woodiwiss A J, Norton G R
Abstract excerpt
AIM: We evaluated whether any one variant of genes that encode for substances that could modulate renin-angiotensin-aldosterone (RAA) system activity can account for a substantial proportion of the variability of plasma RAA system profiles in black South African hypertensives (HTs). METHODS: Plasma renin activity (PRA) and aldosterone concentrations (ALD) were determined in 59 black subjects with mild-to-moderate...
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