Article
The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma.
American journal of respiratory and critical care medicine - 1 Jul 2000
Israel E, Drazen J M, Liggett S B, Boushey H A, Cherniack R M, Chinchilli V M, Cooper D M, Fahy J V, Fish J E, Ford J G, Kraft M, Kunselman S, Lazarus S C, Lemanske R F, Martin R J, McLean D E, Peters S P, Silverman E K, Sorkness C A, Szefler S J, Weiss S T, Yandava C N
Abstract excerpt
Inhaled beta-adrenergic agonists are the most commonly used medications for the treatment of asthma although there is evidence that regular use may produce adverse effects in some patients. Polymorphisms of the beta(2)-adrenergic receptor (beta(2)-AR) can affect regulation of the receptor. Smaller studies examining the effects of such polymorphisms on the response to beta-agonist therapy have produced...
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