Article
Impact of genetic polymorphisms of the beta2-adrenergic receptor on albuterol bronchodilator pharmacodynamics.
Clinical pharmacology and therapeutics - 1 May 1999
Lima J J, Thomason D B, Mohamed M H, Eberle L V, Self T H, Johnson J A
Abstract excerpt
OBJECTIVE: To determine whether genetic polymorphisms of the beta2-adrenergic receptor gene affect the relationship between albuterol (INN, salbutamol) plasma concentrations and the forced expiratory volume in 1 second (FEV1) in subjects with moderate asthma. METHODS: Sixteen clinically stable pa...
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