Article
Possible protective effects of the Glu27 allele of beta2-adrenergic receptor polymorphism in Thai asthmatic patients.
Asian Pacific journal of allergy and immunology - 1 Jan 2000
Limsuwan Ticha, Thakkinstian Ammarin, Verasertniyom Oravan, Vanichapuntu Monchand, Attia John, Janwityanujit Suchela, Nantiruj Kanokrat
Abstract excerpt
The genetic polymorphisms at the 16th (Arg--> Gly) and 27th (Gln-->Glu) amino acid positions of the beta2-adrenergic receptor (ADRB2) may be linked to various asthma-related phenotypes. These include the adverse effects on lung function known to occur following the regular use of albuterol. The study aimed to determine the association between these two ADRB2 SNPs, their haplotypes and the phenotypes in Thai...
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