Article
A DNA-based detection and screening system for identifying HLA class I expression variants by sequence-specific primers.
Tissue antigens - 1 May 1999
Bunce M, Procter J, Welsh K I
Abstract excerpt
Molecular methods are now commonplace for HLA typing and they have replaced traditional serological methods in many histocompatibility laboratories. A consequence of reliance on molecular methods using primers or probes based on existing sequence information is that unsequenced or partially-sequenced null, or low expressed variants are not discriminated from expressed alleles. Failure to identify null alleles...
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