Article
Genetic and epigenetic influence on EAE phenotypes induced with different encephalitogenic peptides.
Journal of neuroimmunology - 1 Aug 2000
Sobel R A
Abstract excerpt
Different encephalitogenic peptides can induce two distinct experimental autoimmune encephalomyelitis (EAE) phenotypes in different mouse strains. To determine whether different peptides induce distinct phenotypes in genetically identical mice, parental strain and (SJLXC3H/HeJ)F1 mice were sensitized with myelin proteolipid protein peptide p139-151 or p215-232. p139-151 was non-encephalitogenic in C3H/HeJ mice...
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