Article
Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatibility complex (MHC) haplotype-related.
Journal of neuropathology and experimental neurology - 1 Dec 2006
Storch Maria K, Bauer Jan, Linington Christopher, Olsson Tomas, Weissert Robert, Lassmann Hans
Abstract excerpt
In recent years, a number of histopathologic studies revealed the presence of cortical demyelination in multiple sclerosis (MS). The underlying mechanisms responsible for cortical demyelination are unresolved. Recently, the presence of cortical lesions in autoimmune encephalomyelitis (EAE) induced in marmosets and Lewis rats has been demonstrated. So far, it is not known whether cortical demyelinated lesions are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
