Different susceptibility to smoking-induced DNA damage among male and female lung cancer patients.

Article

Different susceptibility to smoking-induced DNA damage among male and female lung cancer patients.

Cancer research - 15 Nov 1994

Ryberg D, Hewer A, Phillips D H, Haugen A

Abstract excerpt

The levels of aromatic/hydrophobic DNA adducts were analyzed in normal lung tissue from 63 lung cancer patients and examined in relation to exposure and genetic factors. Adduct levels were significantly higher in smokers than in nonsmokers, but among smokers the number of cigarettes smoked per da...

Topics

Carcinoma, Non-Small-Cell Lung
DNA Adducts
DNA Damage
Disease Susceptibility
Female
Gene Deletion
Genotype
Glutathione Transferase
Humans
Lung
Lung Neoplasms
Male
Regression Analysis
Sex Factors
Smoking
Time Factors

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