Article
Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization.
The EMBO journal - 17 Jul 2000
Lemos C L, Sampaio P, Maiato H, Costa M, Omel'yanchuk L V, Liberal V, Sunkel C E
Abstract excerpt
Through mutational analysis in Drosopjila we have identified the gene multiple asters (mast), which encodes a new 165 kDa protein. mast mutant neuroblasts are highly polyploid and show severe mitotic abnormalities including the formation of mono- and multi-polar spindles organized by an irregular...
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