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Article

Evaluating gene x psychological risk factor effects in the pathogenesis of anxiety: a new model approach.

Journal of abnormal psychology - 1 May 2000

Schmidt N B, Storey J, Greenberg B D, Santiago H T, Li Q, Murphy D L

Abstract excerpt

The present study evaluated the singular and interactive effects of a functional polymorphism (variation) in the serotonin transporter (5-HTT) gene and a psychological trait (anxiety sensitivity [AS], i.e., fear of arousal symptoms) in predicting subjective and physiological responses to a 35% carbon dioxide (CO2) challenge in a community sample (N = 72). Genotypes were divided into 2 groups in accord with prior...

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Source

Identifiers

PMID: 10895569

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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