Article
Significance of the CAG repeat polymorphism of the androgen receptor gene in prostate cancer progression.
The Journal of urology - 1 Aug 2000
Nam R K, Elhaji Y, Krahn M D, Hakimi J, Ho M, Chu W, Sweet J, Trachtenberg J, Jewett M A, Narod S A
Abstract excerpt
PURPOSE: The CAG repeat polymorphism of the androgen receptor gene has been associated with an increased prostate cancer risk, and the repeat length correlated with cancer stage and grade at presentation. Men with an allele length of </= 18 CAG repeats have a 2-fold increase in risk for high-stage or high-grade prostate cancer, compared with patients with a longer CAG repeat. We examined the significance of the...
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