Article
The impact of CAG repeats in exon 1 of the androgen receptor on disease progression after prostatectomy.
Cancer - 1 Feb 2005
Powell Isaac J, Land Susan J, Dey Jyotirmoy, Heilbrun Lance K, Hughes Mark R, Sakr Wael, Everson Richard B
Abstract excerpt
BACKGROUND: The authors examined the impact of the number of CAG repeats in exon 1 of the androgen receptor on disease progression among men with prostate carcinoma after prostatectomy. This polymorphism has been associated with alterations in activity of the androgen receptor in in vitro systems and with the risk of clinically diagnosed prostate carcinoma in some epidemiologic studies. An earlier series found...
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