Article
Relation of the bi-allelic NcoI restriction fragment length polymorphism within the tumour necrosis factor B gene to the development of mediastinitis.
The European journal of surgery. Supplement. : = Acta chirurgica. Supplement - 1 Jan 1999
Schade F U, Stüber F, Börgermann J, Majetschak M
Abstract excerpt
During recent years the dual role of endogenous inflammatory mediators such as tumour necrosis factor (TNF) has become evident. While TNF has been recognised to possess a great detrimental potential, for example in the case of sepsis, it is on the other hand an integral component of an adequate immune response to bacterial invasion. These different properties of TNF and others seem to be dependent mainly on the...
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