Article
Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations.
Molecular psychiatry - 1 May 2000
Vandenbergh D J, Thompson M D, Cook E H, Bendahhou E, Nguyen T, Krasowski M D, Zarrabian D, Comings D, Sellers E M, Tyndale R F, George S R, O'Dowd B F, Uhl G R
Abstract excerpt
The dopamine transporter (DAT) provides major regulation of the synaptic levels of dopamine and is a principal target of psychostimulant drugs. Associations between DAT gene polymorphisms and human disorders with possible links to dopaminergic neurotransmission, including attention-deficit/hyperactivity disorder (ADHD) and consequences of cocaine and alcohol administration, have been reported. We now report...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.