Article
Systematic screening for DNA sequence variation in the coding region of the human dopamine transporter gene (DAT1).
Molecular psychiatry - 1 May 2000
Grünhage F, Schulze T G, Müller D J, Lanczik M, Franzek E, Albus M, Borrmann-Hassenbach M, Knapp M, Cichon S, Maier W, Rietschel M, Propping P, Nöthen M M
Abstract excerpt
The dopamine transporter (DAT) plays a central role in dopaminergic neurotransmission in the human brain. Genetic association studies have used a variable number of tandem repeat (VNTR) polymorphism in the 3'-flanking region of the dopamine transporter gene (DAT1) to implicate the DAT in the development of various neuropsychiatric disorders. In this study, we have examined the possibility that a mutation exists...
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