Article
Determinants of mild clinical symptoms in cystic fibrosis patients. Residual chloride secretion measured in rectal biopsies in relation to the genotype.
The Journal of clinical investigation - 1 Feb 1994
Veeze H J, Halley D J, Bijman J, de Jongste J C, de Jonge H R, Sinaasappel M
Abstract excerpt
Previous Ussing chamber measurements of secretagogue-provoked changes in short circuit current in rectal suction biopsies of cystic fibrosis (CF) patients showed that in a minority of patients chloride secretion in response to cholinergic agonists is reduced but not completely absent. To assess a possible relationship between this phenomenon and both the genotype and the phenotype, we performed Ussing chamber...
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