Article
The superfamily of heptahelical receptors.
Nature cell biology - 1 Jul 2000
Lefkowitz R J
Abstract excerpt
Despite a growing appreciation of functional analogies between visual and hormonal signalling systems in the early 1980s, the discovery of the close structural relationship between rhodopsin and the beta2-adrenergic receptor, and of the existence of a larger 'superfamily' of such receptors, came as a total surprise. Here I provide a personal perspective on events leading up to and flowing from this exciting...
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