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Article

Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells.

The Journal of biological chemistry - 3 May 2002

Tang Shaohua, Bhatia Bobby, Maldonado Carlos J, Yang Peiying, Newman Robert A, Liu Junwei, Chandra Dhyan, Traag Jeanine, Klein Russell D, Fischer Susan M, Chopra Dharam, Shen Jianjun, Zhau Haiyen E, Chung Leland W K, Tang Dean G

Abstract excerpt

15-Lipoxygenase 2 (15-LOX2) is a recently cloned human lipoxygenase that shows tissue-restricted expression in prostate, lung, skin, and cornea. The protein level and enzymatic activity of 15-LOX2 have been shown to be down-regulated in prostate cancers compared with normal and benign prostate ti...

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Identifiers

PMID: 11839751
DOI: 10.1074/jbc.M111936200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11839751-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells.PMID 11839751Read ↗

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