Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of the US3 gene product of BHV-1 as a protein kinase and characterization of BHV-1 mutants of the US3 gene.

Virus research - 1 Jan 1999

Takashima Y, Tamura H, Xuan X, Otsuka H

Abstract excerpt

We have identified the product of the US3 gene of bovine herpes virus type 1 (BHV-1), which is homologous to the herpes simplex virus type 1 (HSV-1) US3 protein kinase (PK) gene. The antibodies against the BHV-1 US3 gene product reacted with a 58 kDa polypeptide in BHV-1 infected cells and the 58 kDa polypeptide purified by immuno-precipitation demonstrated PK activity. Recent reports indicating that the US3 gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Western
Share to Cattle
Share to DNA Fragmentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Herpesvirus 1, Bovine

Share to Phosphorylation

Share to Protein Kinases

Share to Viral Proteins

Share to Virion

Source

Identifiers

PMID: 10854163
DOI: 10.1016/s0168-1702(98)00119-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of the US3 gene product of BHV-1 as a protein kinase and characterization of BHV-1 mutants of the US3 gene.PMID 10854163Read ↗

The HSV-1 Us3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members.Semantic proximity Read ↗

Effect of the US3 protein of bovine herpesvirus 5 on the actin cytoskeleton and apoptosis.Semantic proximity Read ↗

Antiapoptotic activity of herpes simplex virus type 2: the role of US3 protein kinase geneSemantic proximity Read ↗

The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virus.Semantic proximity Read ↗

The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD.Semantic proximity Read ↗

The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins.Semantic proximity Read ↗

Herpes Simplex Virus Inhibits Apoptosis through the Action of Two Genes, Us5 and Us3Semantic proximity Read ↗

The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage.Semantic proximity Read ↗

Expression of herpes simplex virus type 2 US3 affects the Cdc42/Rac pathway and attenuates c-Jun N-terminal kinase activation.Semantic proximity Read ↗

The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B.Semantic proximity Read ↗

Inhibition of N-linked glycosylation causes apoptosis in hamster BHK21 cells.Semantic proximity Read ↗

Characterization of the bovine herpesvirus 1 homolog of the herpes simplex virus 1 UL24 open reading frame.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.