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Article

Inhibition of N-linked glycosylation causes apoptosis in hamster BHK21 cells.

Biochemical and biophysical research communications - 5 Oct 2000

Yoshimi M, Sekiguchi T, Hara N, Nishimoto T

Abstract excerpt

The tsBN7 cell line is one of the temperature-sensitive mutants for cell proliferation derived from hamster BHK21 cell line. It has a mutation in the DAD1 gene and enters apoptosis at the restrictive temperature of 39 degrees C. The defect of Dad1p causes a loss of N-linked glycosylation; therefore, it was thought that an inhibition of N-linked glycosylation induced apoptosis.However, tunicamycin, a potent...

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Source

Identifiers

PMID: 11027576
DOI: 10.1006/bbrc.2000.3565

Genes

DAD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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