Article
Herpes Simplex Virus Inhibits Apoptosis through the Action of Two Genes, Us5 and Us3
1 Nov 1999
Abstract excerpt
Apoptosis of virus-infected cells occurs either as a direct response to viral infection or upon recognition of infection by the host immune response. Apoptosis reduces production of new virus from these cells, and therefore viruses have evolved inhibitory mechanisms. We previously showed that laboratory strains of herpes simplex virus type 1 (HSV-1) protect infected cells from apoptosis induced by cytotoxic T...
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