Article
Effect of the US3 protein of bovine herpesvirus 5 on the actin cytoskeleton and apoptosis.
Veterinary microbiology - 15 Dec 2011
Ladelfa María Fátima, Kotsias Fiorella, Del Médico Zajac María Paula, Van den Broeke Céline, Favoreel Herman, Romera Sonia Alejandra, Calamante Gabriela
Abstract excerpt
The US3 protein is a unique protein kinase only present in the Alphaherpesvirinae subfamily of the herpesviruses. Studies performed with several alphaherpesviruses demonstrated that the US3 protein is involved in cytoskeleton modifications during viral infection and displays anti-apoptotic activity. However, the US3 protein of BoHV-5 has not been studied up to now. As reported for other alphaherpesviruses, our...
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