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Article

Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family.

Molecular and cellular biology - 1 Jul 2000

Poulin G, Lebel M, Chamberland M, Paradis F W, Drouin J

Abstract excerpt

Homeoproteins and basic helix-loop-helix (bHLH) transcription factors are known for their critical role in development and cellular differentiation. The pituitary pro-opiomelanocortin (POMC) gene is a target for factors of both families. Indeed, pituitary-specific transcription of POMC depends on the action of the homeodomain-containing transcription factor Pitx1 and of bHLH heterodimers containing NeuroD1. We...

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Source

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Identifiers

PMID: 10848608
DOI: 10.1128/MCB.20.13.4826-4837.2000
PMCID: PMC85932

Genes

POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family.PMID 10848608Read ↗

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