Hydroperoxide-induced DNA damage and mutations.

doi:10.1016/s0027-5107(00)00019-1

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Article

Hydroperoxide-induced DNA damage and mutations.

Mutation research - 30 May 2000

Termini J

Abstract excerpt

Hydroperoxides (ROOH) are believed to play an important role in the generation of free radical damage in biology. Hydrogen peroxide (R=H) is produced by endogenous metabolic and catabolic processes in cells, while alkyl hydroperoxides (R=lipid, protein, DNA) are produced by free radical chain reactions involving molecular oxygen (autooxidation). The role of metal ions in generating DNA damage from hydroperoxides...

Topics

Animals
Binding Sites
DNA
DNA Damage
Free Radicals
Humans
Hydrogen Peroxide
Metals
Models, Chemical
Mutation
Oxidation-Reduction
Peroxides

Source

Open in PubMed

Identifiers

PMID: 10838137
DOI: 10.1016/s0027-5107(00)00019-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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